Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3762383 | 0.81 | EGLN3 (0.57) | HPGDHSD17B10ALDH1A1LMNAMAPT | |
| SCHEMBL1165232 | 0.80 | SMN1; SMN2 (0.43) | HPGDHSD17B10ALDH1A1KDM4ETP53 | |
| SCHEMBL11084416 | 0.75 | HSP90AA1 (0.55) | HPGDHSD17B10ALDH1A1KDM4ETP53 | |
| SCHEMBL3756602 | 0.75 | SLC40A1 (0.52) | HPGDALDH1A1KDM4ETP53HTT | |
| SCHEMBL8625603 | 0.74 | MAPT (0.62) | HPGDHSD17B10ALDH1A1KDM4ETP53 | |
| SCHEMBL1165214 | 0.73 | EGLN3 (0.59) | HPGDHSD17B10ALDH1A1KDM4ETP53 | |
| SCHEMBL16039856 | 0.73 | TP53 (0.49) | HPGDHSD17B10ALDH1A1KDM4ETP53 | |
| SCHEMBL6985945 | 0.72 | HPGD (0.57) | HPGDHSD17B10ALDH1A1KDM4ETP53 | |
| SCHEMBL29601361 | 0.71 | ALDH1A1 (0.51) | HPGDHSD17B10ALDH1A1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL8374272 | 0.71 | LMNA (0.42) | HPGDHSD17B10ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305154-A1 | Prolyl Hydroxylase Inhibitors | GLAXOSMITHKLINE LLC | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305154-A1 | Prolyl Hydroxylase Inhibitors | HIF1AN, EGLN3, EGLN2 | HPGD 58/4885HSD17B10 507/4885ALDH1A1 158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.