Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11652339 | 1.00 | TSHR (0.50) | TSHRALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL30382526 | 0.79 | ALDH1A1 (0.57) | TSHRALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL1897174 | 0.79 | ALDH1A1 (0.57) | TSHRALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL30970189 | 0.77 | MAPT (0.52) | TSHRALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL13807644 | 0.77 | MAPT (0.49) | TSHRALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL1429398 | 0.77 | TSHR (0.54) | TSHRALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL8746685 | 0.76 | MAPT (0.62) | ALDH1A1LMNAMAPTRAB9ANPC1 | |
| SCHEMBL10870559 | 0.76 | MAPT (0.71) | ALDH1A1LMNAMAPTRAB9ANPC1 | |
| SCHEMBL7111166 | 0.75 | CA1 (0.56) | TSHRALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL28474988 | 0.75 | TSHR (0.53) | TSHRALDH1A1LMNAMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4120689-A | POSTEMERGENT | MONSANTO COMPANY (US) | 1978-10-17 | — | — | US | disclosed |
| US-4083898-A | Process for preparing O-aryl, N-phosphonomethylglycinonitriles | MONSANTO COMPANY (US) | 1978-04-11 | — | — | US | disclosed |
| US-4067719-A | O-Aryl N-phosphonomethylglycinonitriles and the herbicidal use thereof | MONSANTO COMPANY (US) | 1978-01-10 | — | — | US | disclosed |