Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30382526 | 1.00 | ALDH1A1 (0.57) | ALDH1A1MAPK1MAPTTSHRGAA | |
| SCHEMBL6180876 | 0.90 | MERTK (0.52) | ALDH1A1MAPK1MAPTTSHRGAA | |
| SCHEMBL6567485 | 0.89 | PIN1 (0.52) | ALDH1A1MAPK1MAPTGAAL3MBTL1 | |
| SCHEMBL178068 | 0.85 | ALDH1A1 (0.61) | ALDH1A1MAPK1MAPTTSHRNPC1 | |
| SCHEMBL1662886 | 0.84 | ALDH1A1 (0.65) | ALDH1A1MAPK1MAPTTSHRNPC1 | |
| SCHEMBL30970189 | 0.83 | MAPT (0.52) | ALDH1A1MAPTTSHRGAAL3MBTL1 | |
| SCHEMBL11199415 | 0.82 | ALDH1A1 (0.54) | ALDH1A1MAPK1MAPTGAAL3MBTL1 | |
| SCHEMBL14363505 | 0.82 | ALDH1A1 (0.55) | ALDH1A1MAPK1MAPTGAAL3MBTL1 | |
| SCHEMBL10870559 | 0.81 | MAPT (0.71) | ALDH1A1MAPK1MAPTGAAL3MBTL1 | |
| SCHEMBL8746685 | 0.81 | MAPT (0.62) | ALDH1A1MAPTGAAL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109305923-B | Synthetic method of aminoanisole compound | 中国石油化工股份有限公司 | 2022-03-11 | — | — | CN | claimed |
| CN-109305924-B | Synthetic method of aminoanisole compound | 中国石油化工股份有限公司 | 2022-01-04 | — | — | CN | claimed |
| CN-111470991-A | Synthetic method of aminoanisole compound | 中国石油化工股份有限公司 | 2020-07-31 | — | — | CN | claimed |
| CN-111468124-A | Synthetic method of aminoanisole compound | 中国石油化工股份有限公司 | 2020-07-31 | — | — | CN | claimed |
| CN-111470985-A | Synthetic method of aminoanisole compound | 中国石油化工股份有限公司 | 2020-07-31 | — | — | CN | claimed |
| CN-111470986-A | Synthetic method of aminoanisole compound | 中国石油化工股份有限公司 | 2020-07-31 | — | — | CN | claimed |
| CN-109305924-A | A kind of synthetic method of aminobenzoic ethers compound | 中国石油化工股份有限公司 | 2019-02-05 | — | — | CN | claimed |
| CN-109305923-A | A kind of synthetic method of aminobenzoic ethers compound | 中国石油化工股份有限公司 | 2019-02-05 | — | — | CN | claimed |
| CN-102718692-B | Preparation method of 7-bit methyl-5-bit oxygen-substituted indole compounds | SUZHOU HEJIAN MEDICAL TECHNOLOGY CO LTD | 2014-01-08 | — | — | CN | claimed |
| US-11787791-B2 | Inhibitors of VAP-1 | ACUCELA INC. (US) | 2023-10-17 | — | — | US | disclosed |
| US-20230295140-A1 | INHIBITORS OF VAP-1 | ACUCELA INC. | 2023-09-21 | — | — | US | disclosed |
| CN-116116433-A | Supported diatomic catalyst and preparation method and application thereof | 西安理工大学 | 2023-05-16 | — | — | CN | disclosed |
| CN-109988093-B | Amine compound for inhibiting SSAO/VAP-1 and application thereof in medicine | 广东东阳光药业有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-113105475-B | Inhibitors of bruton's tyrosine kinase and methods of use thereof | 詹森药业有限公司 | 2022-09-09 | — | — | CN | disclosed |
| US-4299992-A | Process for the selective hydroxymethylation of nitrotoluenes | REANAL FINOMVEGYSZERGYAR (HU) | 1981-11-10 | — | — | US | disclosed |
| US-4224340-A | Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds | WILLIAM H. RORER, INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4214003-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1980-07-22 | — | — | US | disclosed |
| US-4197314-A | WITH A DIPHENYL NITRONE | WILLIAM H. RORER, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4153722-A | ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE | WILLIAM H. RORER, INC. (US) | 1979-05-08 | — | — | US | disclosed |
| US-3976639-A | Intermediates for indoles | HOFFMANN-LA ROCHE INC. (US) | 1976-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787791-B2 | Inhibitors of VAP-1 | VAPB, VAPA, TOE1 | ALDH1A1 869/4885MAPK1 1527/4885MAPT 2213/4885 |
| US-20230295140-A1 | INHIBITORS OF VAP-1 | VAPB, VAPA, TOE1 | ALDH1A1 869/4885MAPK1 1527/4885MAPT 2213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.