Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 15/20 | 0.37 |
| ▸ | CNR1 | P21554 | 14/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11649389 | 0.93 | THRB (0.40) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL11655697 | 0.88 | THRB (0.42) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL11655278 | 0.86 | HTT (0.43) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL11648861 | 0.84 | THRB (0.43) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL11800633 | 0.84 | CNR1 (0.37) | TSHRCNR2CNR1TRPV1 | |
| SCHEMBL11648102 | 0.83 | TDP1 (0.44) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL11653096 | 0.82 | POLB (0.39) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL11797369 | 0.81 | GAA (0.39) | TSHRTDP1CNR1 | |
| SCHEMBL11668060 | 0.80 | THRB (0.45) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL11654877 | 0.80 | THRB (0.45) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117240-A | CONTAINING ANTIOXIDANT PHENOLIC DERIVATIVES OF ACRYLIC ESTERS AS MONOMERS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-09-26 | — | — | US | disclosed |
| US-3962187-A | STABILIZED POLYMERS OF DITERTIARY ALKYL-4-HYDROXYBENZYLOXY ALKYL ACRYLATES AND DIENES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1976-06-08 | — | — | US | disclosed |