Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MDH1 | P40925 | 3/20 | 0.33 |
| ▸ | MDH2 | P40926 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11655697 | 0.88 | THRB (0.42) | HTTTDP1POLBAPEX1THRB | |
| SCHEMBL11648102 | 0.87 | TDP1 (0.44) | HTTTDP1POLBAPEX1THRB | |
| SCHEMBL11653080 | 0.86 | TSHR (0.43) | HTTTDP1POLBAPEX1THRB | |
| SCHEMBL11649389 | 0.86 | THRB (0.40) | HTTTDP1POLBAPEX1THRB | |
| SCHEMBL11653096 | 0.85 | POLB (0.39) | HTTTDP1POLBAPEX1THRB | |
| SCHEMBL11654877 | 0.83 | THRB (0.45) | HTTTDP1POLBAPEX1THRB | |
| SCHEMBL11668060 | 0.83 | THRB (0.45) | HTTTDP1POLBAPEX1THRB | |
| SCHEMBL11648354 | 0.82 | THRB (0.42) | HTTTDP1POLBAPEX1THRB | |
| SCHEMBL11800906 | 0.82 | ELANE (0.37) | HTTTDP1POLBAPEX1CA1 | |
| SCHEMBL11648518 | 0.82 | THRB (0.49) | THRBTSHRCYP3A4SMN1; SMN2MDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117240-A | CONTAINING ANTIOXIDANT PHENOLIC DERIVATIVES OF ACRYLIC ESTERS AS MONOMERS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-09-26 | — | — | US | disclosed |
| US-3962187-A | STABILIZED POLYMERS OF DITERTIARY ALKYL-4-HYDROXYBENZYLOXY ALKYL ACRYLATES AND DIENES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1976-06-08 | — | — | US | disclosed |