Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 7/20 | 0.42 |
| ▸ | ANPEP | P15144 | 4/20 | 0.42 |
| ▸ | HRH1 | P35367 | 4/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21821598 | 0.79 | SRD5A1 (0.48) | SRD5A1ANPEPCYP1A2TP53RECQL | |
| SCHEMBL6169947 | 0.79 | SIGMAR1 (0.47) | SRD5A1 | |
| SCHEMBL7993604 | 0.79 | SIGMAR1 (0.41) | SRD5A1HTR2AHTR2C | |
| SCHEMBL7706950 | 0.79 | SIGMAR1 (0.47) | SRD5A1 | |
| SCHEMBL6266061 | 0.77 | SIGMAR1 (0.50) | SRD5A1 | |
| SCHEMBL11671198 | 0.74 | SRD5A1 (0.55) | SRD5A1HTR2A | |
| SCHEMBL25795492 | 0.73 | ANPEP (0.43) | HTR2AANPEPCYP1A2CYP2A6SMN1; SMN2 | |
| SCHEMBL300150 | 0.72 | HTR2A (0.50) | HTR2AANPEPHTR2CCYP1A2CYP2A6 | |
| SCHEMBL9393471 | 0.72 | SRD5A1 (0.55) | SRD5A1CYP1A2 | |
| Magnesium SCHEMBL31510119 | 0.72 | SRD5A1 (0.53) | SRD5A1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125718-A | Amino-substituted tetracyclic compounds | AKZONA INCORPORATED (US) | 1978-11-14 | — | — | US | disclosed |
| US-4062840-A | Amino-substituted 1,2,3,4-tetrahydro-9H-tribenzo[b,d,f]azepines | AKZONA INCORPORATED (US) | 1977-12-13 | — | — | US | disclosed |
| US-3950425-A | Amino-substituted tetracyclic compounds | AKZONA INCORPORATED (US) | 1976-04-13 | — | — | US | disclosed |