Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 6/20 | 0.39 |
| ▸ | HTR2C | P28335 | 6/20 | 0.39 |
| ▸ | HTR2B | P41595 | 6/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6169947 | 0.89 | SIGMAR1 (0.47) | SIGMAR1SRD5A1 | |
| SCHEMBL7706950 | 0.89 | SIGMAR1 (0.47) | SIGMAR1SRD5A1 | |
| SCHEMBL7709441 | 0.86 | SIGMAR1 (0.47) | SIGMAR1SRD5A1 | |
| SCHEMBL7709439 | 0.86 | SIGMAR1 (0.47) | SIGMAR1SRD5A1 | |
| SCHEMBL8051810 | 0.86 | SIGMAR1 (0.47) | SIGMAR1SRD5A1 | |
| SCHEMBL6266061 | 0.84 | SIGMAR1 (0.50) | SIGMAR1SRD5A1 | |
| SCHEMBL11653286 | 0.79 | SRD5A1 (0.43) | SRD5A1HTR2AHTR2C | |
| SCHEMBL7091597 | 0.77 | PLAU (0.41) | — | |
| SCHEMBL7091599 | 0.77 | PLAU (0.41) | — | |
| SCHEMBL7091601 | 0.77 | PLAU (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001014334-A1 | FLUORENONE COMPOUNDS WITH MODIFIED 7-POSITION SUBSTITUENTS FOR TREATING AND PREVENTING BRAIN AND SPINAL INJURY | QUESTCOR PHARMACEUTICALS, INC. (US) | 2001-03-01 | — | — | WO | disclosed |
| US-4113726-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1978-09-12 | — | — | US | disclosed |
| US-3984419-A | HYPOTENSIVES | E. R. SQUIBB & SONS, INC. (US) | 1976-10-05 | — | — | US | disclosed |