Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11657643 | 0.88 | PTGER1 (0.40) | GRM2 | |
| SCHEMBL11658907 | 0.86 | FAAH (0.41) | FAAH | |
| SCHEMBL11657549 | 0.84 | NPC1 (0.40) | — | |
| SCHEMBL11654437 | 0.82 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL11732380 | 0.82 | GRM2 (0.38) | GRM2FAAH | |
| SCHEMBL11732372 | 0.82 | FAAH (0.36) | GRM2FAAH | |
| SCHEMBL11656559 | 0.81 | TSHR (0.48) | — | |
| SCHEMBL11657750 | 0.80 | TBXA2R (0.48) | — | |
| SCHEMBL11659488 | 0.80 | HPGD (0.37) | — | |
| SCHEMBL11656949 | 0.80 | TBXA2R (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4126629-A | FERTILITY CONTROL | MERCK & CO., INC. (US) | 1978-11-21 | — | — | US | disclosed |
| US-4061643-A | ANTIFERTILITY | MERCK & CO., INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4020177-A | CONTRACEPTIVES | MERCK & CO., INC. (US) | 1977-04-26 | — | — | US | disclosed |