Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | EIF4E | P06730 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TOP1 | P11387 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.46 |
| ▸ | CDC25B | P30305 | 7/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.46 |
| ▸ | CDC25A | P30304 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066230 | 0.90 | LMNA (0.57) | HTR1ABCHELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL6912407 | 0.75 | LMNA (0.47) | LMNASMN1; SMN2ALDH1A1GLAEIF4E | |
| SCHEMBL20473791 | 0.73 | NT5E (0.52) | HTR1ABCHEPTPN1CDC25BPTPN2 | |
| SCHEMBL18482843 | 0.73 | NT5E (0.52) | HTR1ABCHEPTPN1CDC25BPTPN2 | |
| SCHEMBL12300349 | 0.73 | LMNA (0.47) | LMNASMN1; SMN2ALDH1A1GLAEIF4E | |
| SCHEMBL26658233 | 0.73 | TACR2 (0.44) | HTR1ABCHEPTPN1CDC25BPTPN2 | |
| SCHEMBL6912924 | 0.71 | LMNA (0.57) | LMNASMN1; SMN2ALDH1A1GLAEIF4E | |
| SCHEMBL3898371 | 0.71 | NT5E (0.54) | HTR1ABCHEPTPN1CDC25BPTPN2 | |
| SCHEMBL15968116 | 0.71 | NT5E (0.54) | HTR1ABCHEPTPN1CDC25BPTPN2 | |
| SCHEMBL3898367 | 0.71 | NT5E (0.54) | HTR1ABCHEPTPN1CDC25BPTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE29835-E | PHARMACEUTICAL | ICN PHARMACEUTICALS (US) | 1978-11-14 | — | — | US | disclosed |