Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845560 | 0.84 | PTPN22 (0.42) | TRPM4PKMNQO2CYP2A6CYP1A2 | |
| SCHEMBL3668933 | 0.81 | CYP2A6 (0.44) | NQO2CYP2A6CYP1A2ALDH1A1KDM4E | |
| SCHEMBL17329228 | 0.81 | CASP6 (0.48) | TRPM4PKMNQO2CYP2A6CYP1A2 | |
| SCHEMBL11293469 | 0.79 | CYP2A6 (0.50) | TRPM4PKMNQO2CYP2A6CYP1A2 | |
| SCHEMBL1790663 | 0.79 | TRPM4 (0.56) | TRPM4PKMNQO2CYP1A2ALDH1A1 | |
| SCHEMBL9955133 | 0.79 | ALOX5 (0.46) | TRPM4PKMNQO2CYP2A6CYP1A2 | |
| SCHEMBL31199146 | 0.79 | ALOX5 (0.46) | TRPM4PKMNQO2CYP2A6CYP1A2 | |
| SCHEMBL10907551 | 0.78 | ALOX5 (0.44) | TRPM4PKMNQO2CYP2A6CYP1A2 | |
| SCHEMBL28713468 | 0.76 | CYP1A2 (0.42) | TRPM4PKMNQO2CYP2A6CYP1A2 | |
| SCHEMBL25254332 | 0.76 | CYP2A6 (0.40) | NQO2CYP2A6CYP1A2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4123223-A | Metal-modified polypropylene dyed with azomethine dyes derived from an 0-hydroxy aromatic aldehyde and a 2-aminopyridine | AMERICAN COLOR & CHEMICAL CORPORATION (US) | 1978-10-31 | — | — | US | disclosed |
| US-4051119-A | Azomethine dyes derived from an o-hydroxy aromatic aldehyde and a 2-aminopyridine | AMERICAN COLOR & CHEMICAL CORPORATION (US) | 1977-09-27 | — | — | US | disclosed |