Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 10/20 | 0.70 |
| ▸ | MMP2 | P08253 | 10/20 | 0.70 |
| ▸ | MMP9 | P14780 | 10/20 | 0.70 |
| ▸ | EGFR | P00533 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11648004 | 0.89 | MMP1 (0.70) | MMP1MMP2MMP9EGFRKDM4E | |
| SCHEMBL111461 | 0.87 | MMP1 (0.75) | MMP1MMP2MMP9EGFRKDM4E | |
| SCHEMBL11653968 | 0.85 | MMP1 (0.53) | MMP1MMP2MMP9EGFRKDM4E | |
| SCHEMBL13352117 | 0.82 | MMP1 (0.67) | MMP1MMP2MMP9EGFRKDM4E | |
| N-O-Tolylcinnamamide SCHEMBL2593754 | 0.81 | MMP1 (1.00) | MMP1MMP2MMP9EGFRKDM4E | |
| N-O-Tolylcinnamamide SCHEMBL29844171 | 0.81 | MMP1 (1.00) | MMP1MMP2MMP9EGFRKDM4E | |
| N-O-Tolylcinnamamide SCHEMBL15902545 | 0.81 | MMP1 (1.00) | MMP1MMP2MMP9EGFRKDM4E | |
| N-O-Tolylcinnamamide SCHEMBL2593756 | 0.81 | MMP1 (1.00) | MMP1MMP2MMP9EGFRKDM4E | |
| SCHEMBL14926734 | 0.80 | PYGL (0.53) | SMN1; SMN2TP53MAPTTHRBMEN1 | |
| SCHEMBL11648671 | 0.80 | TP53 (0.55) | MMP1MMP2MMP9EGFRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4130661-A | ANTICOCCIDIAL | MERCK & CO., INC. (US) | 1978-12-19 | — | — | US | claimed |
| US-4130661-A | ANTICOCCIDIAL | MERCK & CO., INC. (US) | 1978-12-19 | — | — | US | disclosed |