Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.48 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GPR88 | Q9GZN0 | 5/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11652659 | 1.00 | ADRB1 (0.48) | ADRB1ADRB3BCAT2KDM4EL3MBTL1 | |
| SCHEMBL11652087 | 1.00 | ADRB1 (0.48) | ADRB1ADRB3BCAT2KDM4EL3MBTL1 | |
| SCHEMBL11655170 | 0.78 | GPR88 (0.43) | L3MBTL1GPR88 | |
| SCHEMBL11655464 | 0.78 | GPR88 (0.43) | L3MBTL1GPR88 | |
| SCHEMBL11654029 | 0.78 | GPR88 (0.43) | L3MBTL1GPR88 | |
| SCHEMBL9559761 | 0.77 | GRM7 (0.51) | L3MBTL1GPR88 | |
| Acetic Acid SCHEMBL11142923 | 0.76 | MEN1 (0.57) | ADRB1ADRB3BCAT2KDM4EL3MBTL1 | |
| SCHEMBL10685645 | 0.75 | KDM4E (0.63) | ADRB1ADRB3BCAT2KDM4EL3MBTL1 | |
| SCHEMBL18885406 | 0.75 | GPR88 (0.53) | L3MBTL1GPR88 | |
| SCHEMBL8016181 | 0.75 | GPR88 (0.53) | L3MBTL1GPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117157-A | TREATMENT OF CARDIOVASCULAR DISORDERS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-09-26 | — | — | US | disclosed |