Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.46 |
| ▸ | MEN1 | O00255 | 11/20 | 0.46 |
| ▸ | USP2 | O75604 | 3/20 | 0.46 |
| ▸ | IDE | P14735 | 2/20 | 0.46 |
| ▸ | CRHBP | P24387 | 2/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.46 |
| ▸ | HTT | P42858 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 5/20 | 0.43 |
| ▸ | RECQL | P46063 | 3/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11656071 | 1.00 | MAPT (0.46) | MAPTKMT2AMEN1USP2IDE | |
| SCHEMBL11686903 | 0.91 | ALDH1A1 (0.41) | MAPTKMT2AMEN1USP2IDE | |
| SCHEMBL11686919 | 0.91 | ALDH1A1 (0.41) | MAPTKMT2AMEN1USP2IDE | |
| SCHEMBL11631621 | 0.85 | MAPT (0.44) | MAPTKMT2AMEN1USP2IDE | |
| SCHEMBL11631622 | 0.85 | MAPT (0.44) | MAPTKMT2AMEN1USP2IDE | |
| SCHEMBL11592460 | 0.81 | KMT2A (0.41) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL11592457 | 0.81 | KMT2A (0.41) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL11591438 | 0.73 | KMT2A (0.41) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL10532021 | 0.72 | MEN1 (0.56) | MAPTKMT2AMEN1USP2IDE | |
| SCHEMBL9618912 | 0.72 | MEN1 (0.56) | MAPTKMT2AMEN1USP2IDE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4081279-A | Photothermographic materials containing radiation sensitive quinone compounds and nitrobenzylidene dyes | EASTMAN KODAK COMPANY (US) | 1978-03-28 | — | — | US | disclosed |