SCHEMBL9618912

SCHEMBL9618912

CCN1C(=O)C(=Cc2ccc([N+](=O)[O-])cc2[N+](=O)[O-])SC1=S

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 10/20 0.56
▸ KMT2A Q03164 10/20 0.56
▸ ALDH1A1 P00352 7/20 0.56
▸ MAPT P10636 5/20 0.56
▸ MAPK1 P28482 2/20 0.56
▸ TDP1 Q9NUW8 1/20 0.56
▸ PLG P00747 1/20 0.56
▸ POLB P06746 5/20 0.54
▸ BLM P54132 3/20 0.54
▸ NPC1 O15118 1/20 0.52
▸ LMNA P02545 1/20 0.52
▸ IDE P14735 1/20 0.52
▸ ALOX12 P18054 1/20 0.52
▸ TNNI3 P19429 1/20 0.52
▸ TNNT2 P45379 1/20 0.52
▸ RAB9A P51151 1/20 0.52
▸ TNNC1 P63316 1/20 0.52
▸ CTRC Q99895 2/20 0.50
▸ NOD2 Q9HC29 1/20 0.48
▸ USP2 O75604 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10532021 1.00 MEN1 (0.56) MEN1KMT2AALDH1A1MAPTMAPK1
SCHEMBL11147680 0.81 TNFRSF1A (0.44) MEN1KMT2AALDH1A1MAPTMAPK1
SCHEMBL9785899 0.81 PPARG (0.61) MEN1KMT2AALDH1A1MAPTMAPK1
SCHEMBL11686919 0.74 ALDH1A1 (0.41) MEN1KMT2AALDH1A1MAPTMAPK1
SCHEMBL11686903 0.74 ALDH1A1 (0.41) MEN1KMT2AALDH1A1MAPTMAPK1
SCHEMBL8210695 0.73 STAT3 (0.60) MEN1KMT2AALDH1A1MAPTTDP1
SCHEMBL11773179 0.72 MEN1 (0.52) MEN1KMT2AALDH1A1MAPTMAPK1
SCHEMBL10438698 0.72 CRHBP (0.64) MEN1KMT2AALDH1A1MAPTPOLB
SCHEMBL13779295 0.72 PDE4B (0.58) MEN1KMT2AALDH1A1MAPTMAPK1
SCHEMBL11656068 0.72 MAPT (0.46) MEN1KMT2AALDH1A1MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3970459-A Process for developing a direct reversal silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 — — US claimed
EP-0300382-B1 PHOTOGRAPHIC EMULSION AND ELEMENT EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-01-08 — — EP disclosed
US-4808516-A HIGH SPEED, CONTRAST EASTMAN KODAK COMPANY (US) 1989-02-28 — — US disclosed
EP-0300382-A1 Photographic emulsion and element EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-01-25 — — EP disclosed
US-4259439-A DIMETHINECYANINE DYE SENSITIZER MITSUBISHI PAPER MILLS, LTD. (JP) 1981-03-31 — — US disclosed
US-4147554-A 5,6-DIHYDRO-PYRROLO(2,1-A)ISOQUINOLINES MITSUBISHI PAPER MILLS, LTD. (JP) 1979-04-03 — — US disclosed
US-RE29930-E HIGH SPEED EASTMAN KODAK COMPANY (US) 1979-03-13 — — US disclosed
US-4097285-A CYANINE DYE MITSUBISHI PAPER MILLS, LTD. (JA) 1978-06-27 — — US disclosed
US-RE29575-E Cubic regular grain photographic reversal emulsions EASTMAN KODAK COMPANY (US) 1978-03-14 — — US disclosed
US-4011081-A DIRECT-POSITIVE DOUBLE EXPOSURE PROCESS UTILIZING A PRIMITIVE, UNFOGGED SILVER HALIDE EMULSION CONTAINING AN ELECTRON ACCEPTOR EASTMAN KODAK COMPANY (US) 1977-03-08 — — US disclosed
US-3970459-A Process for developing a direct reversal silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 — — US disclosed
US-3970461-A Fogged, direct-positive silver halide emulsion containing carbocyanine dye having indolenine nucleus FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 — — US disclosed
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