SCHEMBL1165645

SCHEMBL1165645

CCCCC(CC)CNC(=O)CO

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.53
ALDH1A1 P00352 5/20 0.53
CYP3A4 P08684 2/20 0.53
HTT P42858 3/20 0.49
GLA P06280 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
LMNA P02545 2/20 0.46
CA2 P00918 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
POLB P06746 1/20 0.46
MAPK1 P28482 1/20 0.46
TDP1 Q9NUW8 2/20 0.42
ATM Q13315 1/20 0.42
KMT2A Q03164 2/20 0.42
HRH4 Q9H3N8 1/20 0.40
HRH3 Q9Y5N1 1/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
MMP9 P14780 1/20 0.40
MMP8 P22894 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16312317 0.89 TSHR (0.57) TSHRALDH1A1CYP3A4HTTGLA
SCHEMBL8600740 0.87 TSHR (0.55) TSHRALDH1A1CYP3A4HTTGLA
SCHEMBL8515067 0.87 TSHR (0.55) TSHRALDH1A1CYP3A4HTTGLA
SCHEMBL11663143 0.85 TSHR (0.53) TSHRALDH1A1CYP3A4HTTGLA
SCHEMBL14836356 0.85 TSHR (0.53) TSHRALDH1A1CYP3A4HTTGLA
SCHEMBL11235364 0.84 TSHR (0.48) TSHRALDH1A1CYP3A4HTTGLA
SCHEMBL17122532 0.84 TSHR (0.34) TSHRALDH1A1HTTGLAL3MBTL1
SCHEMBL1515649 0.84 TSHR (0.52) TSHRALDH1A1CYP3A4HTTGLA
SCHEMBL362747 0.84 TSHR (0.52) TSHRALDH1A1CYP3A4HTTGLA
SCHEMBL28673768 0.84 FAAH (0.53) TSHRALDH1A1CYP3A4HTTGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2891701-B1 LUBRICATING COMPOSITION CONTAINING A CORROSION INHIBITOR LUBRIZOL CORP (US) 2019-07-03 EP disclosed
EP-2891700-B1 LUBRICATING COMPOSITION CONTAINING AN ANTIWEAR AGENT LUBRIZOL CORP (US) 2019-06-26 EP disclosed
EP-2467457-B1 LUBRICATING COMPOSITION CONTAINING AN ANTIWEAR AGENT LUBRIZOL CORP (US) 2015-07-22 EP disclosed
EP-2891701-A1 Lubricating composition containing a corrosion inhibitor The Lubrizol Corporation (US) 2015-07-08 EP disclosed
EP-2891700-A1 Lubricating composition containing an antiwear agent The Lubrizol Corporation (US) 2015-07-08 EP disclosed
US-8728996-B2 Lubricating composition containing an antiwear agent THE LUBRIZOL CORPORATION (US) 2014-05-20 US disclosed
US-8722599-B2 Lubricating compositions containing an antiwear agent THE LUBRIZOL CORPORATION (US) 2014-05-13 US disclosed
US-20130303417-A1 Lubricating Compositions Containing An Antiwear Agent THE LUBRIZOL CORPORATION (US) 2013-11-14 US disclosed
US-20130296208-A1 Lubricating Composition Containing An Antiwear Agent THE LUBRIZOL CORPORATION (US) 2013-11-07 US disclosed
US-8557755-B2 Lubricating composition containing an antiwear agent THE LUBRIZOL CORPORATION (US) 2013-10-15 US disclosed
US-8530395-B1 Lubricating composition containing an antiwear agent THE LUBRIZOL CORPORATION (US) 2013-09-10 US disclosed
US-20130157914-A1 Lubricating Composition Containing an Antiwear Agent THE LUBRIZOL CORPORATION (US) 2013-06-20 US disclosed
US-8404625-B2 Lubricating composition containing an antiwear agent THE LUBRIZOL CORPORATION (US) 2013-03-26 US disclosed
US-20120202726-A1 Lubricating Composition Containing an Antiwear Agent THE LUBRIZOL CORPORATION (US) 2012-08-09 US disclosed
EP-2467457-A1 LUBRICATING COMPOSITION CONTAINING AN ANTIWEAR AGENT The Lubrizol Corporation (US) 2012-06-27 EP disclosed
WO-2011022317-A1 LUBRICATING COMPOSITION CONTAINING AN ANTIWEAR AGENT THE LUBRIZOL CORPORATION (US) 2011-02-24 WO disclosed