Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 9/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.44 |
| ▸ | HTR1A | P08908 | 5/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HTR2C | P28335 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | HTR2B | P41595 | 3/20 | 0.44 |
| ▸ | NR2E1 | Q9Y466 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | HTR6 | P50406 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | SCN1A | P35498 | 2/20 | 0.44 |
| ▸ | SLC10A1 | Q14973 | 2/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11631654 | 0.89 | ADRB2 (0.47) | ADRB2ADRB1ADRB3CYP1A2HTR1A | |
| Indenolol SCHEMBL79023 | 0.89 | ADRB2 (0.56) | ADRB2ADRB1ADRB3CYP1A2HTR1A | |
| Indenolol SCHEMBL79021 | 0.89 | ADRB2 (0.56) | ADRB2ADRB1ADRB3CYP1A2HTR1A | |
| Indenolol SCHEMBL349116 | 0.88 | ADRB2 (0.57) | ADRB2ADRB1ADRB3CYP1A2HTR1A | |
| Indenolol SCHEMBL349114 | 0.88 | ADRB2 (0.57) | ADRB2ADRB1ADRB3CYP1A2HTR1A | |
| Indenolol SCHEMBL1650473 | 0.87 | ADRB2 (0.54) | ADRB2ADRB1ADRB3CYP1A2HTR1A | |
| Hydrochloric Acid SCHEMBL11659927 | 0.86 | ADRB2 (0.46) | ADRB2ADRB1ADRB3CYP1A2HTR1A | |
| SCHEMBL11632993 | 0.82 | ABCB1 (0.48) | ADRB2ADRB1ADRB3CYP1A2SIGMAR1 | |
| SCHEMBL11754160 | 0.82 | ALOX15 (0.41) | ADRB2ADRB1ADRB3CYP1A2HTR1A | |
| SCHEMBL11657805 | 0.81 | ADRB2 (0.60) | ADRB2ADRB1ADRB3CYP1A2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4127675-A | BETA-RECEPTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1978-11-28 | — | — | US | disclosed |
| US-4045482-A | ADRENERGIC B-RECEPTOR BLOCKING AGENTS | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JA) | 1977-08-30 | — | — | US | disclosed |