Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MERTK | Q12866 | 5/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 4/20 | 0.37 |
| ▸ | FLT3 | P36888 | 3/20 | 0.37 |
| ▸ | GAS6 | Q14393 | 3/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11652757 | 0.79 | LMNA (0.42) | CYP1A2LMNACYP2D6HTTSMN1; SMN2 | |
| SCHEMBL1898299 | 0.73 | LMNA (0.70) | CYP1A2LMNACYP2D6HTTSMN1; SMN2 | |
| SCHEMBL10593462 | 0.72 | HTT (0.41) | CYP1A2LMNAHTTADORA3CYP2C9 | |
| SCHEMBL11586399 | 0.71 | LMNA (0.47) | CYP1A2LMNASMN1; SMN2CDK5CDK5R1 | |
| SCHEMBL11654039 | 0.69 | ESR1 (0.46) | CYP1A2LMNACYP2D6HTTSMN1; SMN2 | |
| SCHEMBL10898323 | 0.67 | MEN1 (0.44) | CYP1A2LMNAHTTADORA3CYP2C9 | |
| SCHEMBL14341081 | 0.65 | LMNA (0.42) | CYP1A2LMNAHTTMERTKADORA3 | |
| SCHEMBL11364615 | 0.65 | ESR1 (0.44) | LMNAMAPTKMT2A | |
| SCHEMBL19928665 | 0.65 | HRH4 (0.49) | CYP1A2CYP2D6MERTKTYRO3FLT3 | |
| SCHEMBL763729 | 0.65 | TLR8 (0.42) | CYP2D6SMN1; SMN2CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4082535-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1978-04-04 | — | — | US | disclosed |