Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11658861 | 0.86 | FFAR1 (0.50) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3852942 | 0.83 | HDAC1 (0.56) | MAPTNPC1POLBALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL3848965 | 0.81 | HDAC1 (0.54) | MAPTNPC1POLBALDH1A1HSD17B10 | |
| SCHEMBL11109551 | 0.80 | MAPT (0.54) | PTGS2MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7333688 | 0.80 | MAPT (0.59) | PTGS2MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11660894 | 0.79 | MAPT (0.51) | PTGS2MAPTPOLBALDH1A1CYP2C9 | |
| SCHEMBL11661378 | 0.79 | ALDH1A1 (0.47) | PTGS2MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2116437 | 0.79 | PTGS2 (0.66) | PTGS2MAPTSMN1; SMN2POLBALDH1A1 | |
| SCHEMBL2009866 | 0.78 | GSK3B (0.64) | PTGS2MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2012060 | 0.78 | MAPT (0.53) | PTGS2MAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4105790-A | ANTICOAGULANTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-08-08 | — | — | US | disclosed |