Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.59 |
| ▸ | BCHE | P06276 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.49 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11657877 | 0.84 | ALDH1A1 (0.70) | MAOBBCHEMAPTALDH1A1LMNA | |
| SCHEMBL15807392 | 0.83 | MAOB (0.72) | MAOBBCHEMAPTCYP1B1ALDH1A1 | |
| SCHEMBL29083859 | 0.83 | TYR (0.65) | MAOBBCHEMAPTCYP1B1ALDH1A1 | |
| SCHEMBL27631290 | 0.83 | TYR (0.65) | MAOBBCHEMAPTCYP1B1ALDH1A1 | |
| SCHEMBL11655661 | 0.80 | MAOB (0.56) | MAOBBCHEMAPTCYP1B1ALDH1A1 | |
| SCHEMBL9779492 | 0.79 | MAPT (0.70) | MAOBBCHEMAPTCYP1B1ALDH1A1 | |
| SCHEMBL9779489 | 0.79 | MAPT (0.70) | MAOBBCHEMAPTCYP1B1ALDH1A1 | |
| SCHEMBL14317397 | 0.78 | MAOB (0.56) | MAOBBCHEMAPTCYP1B1ALDH1A1 | |
| SCHEMBL11652456 | 0.77 | MAPT (0.55) | MAOBBCHEMAPTCYP1B1ALDH1A1 | |
| SCHEMBL28346511 | 0.76 | PTGDR2 (0.55) | MAOBBCHEMAPTCYP1B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4128576-A | O-Aroylvinyl benzoyl chlorides | MONSANTO COMPANY (US) | 1978-12-05 | — | — | US | disclosed |