Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14280369 | 0.87 | MAOB (0.55) | MAOBCYP1B1MAPTTYRMAPK1 | |
| SCHEMBL656139 | 0.83 | LMNA (0.70) | MAOBCYP1B1MAPTTYRMAPK1 | |
| SCHEMBL656140 | 0.83 | LMNA (0.70) | MAOBCYP1B1MAPTTYRMAPK1 | |
| SCHEMBL11652456 | 0.83 | MAPT (0.55) | MAOBCYP1B1MAPTTYRMAPK1 | |
| SCHEMBL27969144 | 0.82 | MAOB (0.56) | MAOBCYP1B1MAPTTYRMAPK1 | |
| SCHEMBL29837044 | 0.82 | TYR (0.72) | MAOBCYP1B1MAPTTYRMAPK1 | |
| SCHEMBL21647110 | 0.82 | TYR (0.72) | MAOBCYP1B1MAPTTYRMAPK1 | |
| SCHEMBL21647126 | 0.82 | TYR (0.72) | MAOBCYP1B1MAPTTYRMAPK1 | |
| SCHEMBL11655651 | 0.81 | MAOB (0.55) | MAOBCYP1B1MAPTMAPK1AR | |
| SCHEMBL11657882 | 0.80 | MAOB (0.59) | MAOBCYP1B1MAPTTYRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4128576-A | O-Aroylvinyl benzoyl chlorides | MONSANTO COMPANY (US) | 1978-12-05 | — | — | US | disclosed |