Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.55 |
| ▸ | DAO | P14920 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.45 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15073453 | 0.81 | DAO (0.46) | DHODHDAOFLT3ADORA2BADORA1 | |
| SCHEMBL4884445 | 0.77 | DHODH (0.55) | DHODHDAONPC1RAB9ATUBB4A | |
| SCHEMBL11659848 | 0.76 | DHODH (0.48) | DHODHDAONPC1RAB9ATUBB4A | |
| SCHEMBL12324064 | 0.76 | NPC1 (0.59) | DHODHNPC1RAB9AADORA2BADORA3 | |
| SCHEMBL5673146 | 0.75 | DAO (0.60) | DAOFLT3KDM4EALDH1A1HPGD | |
| SCHEMBL28283952 | 0.75 | DHODH (0.57) | DHODHNPC1RAB9ATUBB4ATUBB | |
| SCHEMBL24988650 | 0.75 | CTSV (0.45) | DHODHNPC1RAB9AADORA2BADORA3 | |
| SCHEMBL7650453 | 0.74 | DHODH (0.55) | DHODHDAONPC1RAB9ATUBB4A | |
| SCHEMBL20496374 | 0.74 | DHODH (0.55) | DHODHNPC1RAB9ATUBB4ATUBB | |
| SCHEMBL16835575 | 0.74 | DHODH (0.55) | DHODHNPC1RAB9ATUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4104268-A | POLYACRYLONITRILE, POLYESTERS, POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-01 | — | — | US | disclosed |
| US-4006127-A | Cationic diazacyanine dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-02-01 | — | — | US | disclosed |