Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 2/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11058171 | 0.71 | — | — | |
| SCHEMBL11061815 | 0.69 | — | — | |
| SCHEMBL28120094 | 0.67 | PDE4D (0.30) | PDE4D | |
| SCHEMBL15777023 | 0.66 | PDE4D (0.57) | PDE4DDYRK1ALMNAL3MBTL1CYP2C19 | |
| SCHEMBL11655985 | 0.66 | KDM4E (0.42) | DYRK1ALMNAL3MBTL1KDR | |
| SCHEMBL15174259 | 0.64 | KDM4E (0.39) | LMNAMEN1KMT2A | |
| SCHEMBL11174076 | 0.63 | MYC (0.36) | MEN1KMT2A | |
| SCHEMBL11654684 | 0.62 | LMNA (0.37) | LMNA | |
| SCHEMBL10957826 | 0.62 | POLB (0.36) | DYRK1A | |
| SCHEMBL4414120 | 0.62 | PDE4D (0.39) | PDE4DDYRK1ALMNAL3MBTL1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4108982-A | DIURETICS, HYPOTENSIVE AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1978-08-22 | — | — | US | disclosed |