Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NMT1 | P30419 | 3/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | LTK | P29376 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11654684 | 0.78 | LMNA (0.37) | KDM4EALDH1A1GAALMNAHTT | |
| SCHEMBL11656600 | 0.76 | MAPT (0.41) | KDM4EALDH1A1GAAKDRCSNK1A1 | |
| SCHEMBL11665652 | 0.73 | SMN1; SMN2 (0.50) | KDM4EALDH1A1TSHRLMNAHTT | |
| SCHEMBL11657656 | 0.72 | HPGD (0.37) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL11657778 | 0.71 | LMNA (0.44) | ALDH1A1TSHRHSD17B10LMNAHTT | |
| SCHEMBL11655639 | 0.70 | POLB (0.57) | KDM4EALDH1A1GAALMNANPC1 | |
| SCHEMBL11660728 | 0.70 | GAA (0.55) | ALDH1A1GAATSHRLMNAHTT | |
| SCHEMBL11652455 | 0.70 | PDE4B (0.51) | KDM4EALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL11654025 | 0.70 | ALDH1A1 (0.46) | ALDH1A1GAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL11058171 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4108982-A | DIURETICS, HYPOTENSIVE AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1978-08-22 | — | — | US | disclosed |