Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11649748 | 0.88 | NAMPT (0.40) | NAMPTGAANPSR1RXFP1CSNK2A2 | |
| SCHEMBL11656613 | 0.83 | GAA (0.41) | NAMPTGAANPSR1RXFP1CSNK2A2 | |
| SCHEMBL11648634 | 0.80 | GAA (0.47) | NAMPTGAANPSR1RXFP1KDM4E | |
| SCHEMBL11652486 | 0.79 | KDM4E (0.52) | GAANPSR1RXFP1CSNK2A2KDR | |
| SCHEMBL11653068 | 0.79 | KDM4E (0.52) | GAANPSR1RXFP1CSNK2A2KDR | |
| SCHEMBL11652981 | 0.79 | KDM4E (0.52) | GAANPSR1RXFP1CSNK2A2KDR | |
| SCHEMBL11652714 | 0.79 | KDM4E (0.52) | GAANPSR1RXFP1CSNK2A2KDR | |
| SCHEMBL11652618 | 0.79 | KDM4E (0.52) | GAANPSR1RXFP1CSNK2A2KDR | |
| SCHEMBL11651262 | 0.78 | GAA (0.42) | NAMPTGAANPSR1RXFP1CSNK2A2 | |
| SCHEMBL26469152 | 0.77 | ALDH1A1 (0.44) | NAMPTGAANPSR1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4089865-A | Certain thiazole compounds | SYNTEX (U.S.A.) INC. (US) | 1978-05-16 | — | — | US | disclosed |
| US-4001421-A | THIAZOLE CARDIOVASCULAR AGENTS | SYNTEX (U.S.A.) INC. (US) | 1977-01-04 | — | — | US | disclosed |