Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | PTGIR | P43119 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | GBA1 | P04062 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MC4R | P32245 | 2/20 | 0.40 |
| ▸ | RAD52 | P43351 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11659457 | 0.85 | KMT2A (0.44) | ERAP1LMNACYP1A2ADRA2ACYP2D6 | |
| SCHEMBL11660165 | 0.85 | EPHX2 (0.40) | ERAP1LMNATSHRCNR1SMN1; SMN2 | |
| SCHEMBL11660626 | 0.79 | SCN5A (0.44) | LMNAKCNH2NPC1SMN1; SMN2MEN1 | |
| SCHEMBL2273066 | 0.70 | NPC1 (0.57) | LMNACYP1A2ADRA2ACYP2D6SLC6A2 | |
| SCHEMBL11657921 | 0.70 | ALDH1A1 (0.37) | ERAP1CYP1A2TP53MAPK1CYP2C19 | |
| SCHEMBL11662776 | 0.70 | EPHX2 (0.39) | LMNAMAPK1TSHRCNR1SMN1; SMN2 | |
| SCHEMBL11658668 | 0.70 | EPHX2 (0.39) | ERAP1LMNAADRB2TSHRHTT | |
| SCHEMBL11662780 | 0.69 | TSHR (0.36) | ERAP1LMNANPC1TSHRSMN1; SMN2 | |
| SCHEMBL11879253 | 0.69 | HTR3A (0.62) | LMNACYP1A2ADRA2ACYP2D6SLC6A2 | |
| SCHEMBL11658427 | 0.69 | GAA (0.44) | LMNACYP1A2CYP2D6NPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088629-A | ADDING A PIPERIDINYL-GUANIDINE | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |