Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 8/20 | 0.45 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11653494 | 0.89 | HTT (0.40) | P2RX4POLBSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11652098 | 0.87 | P2RX4 (0.40) | P2RX4CYP2C8CYP2D6CYP2C9ADRA2B | |
| SCHEMBL11655806 | 0.79 | KMT2A (0.40) | POLBSMN1; SMN2KMT2AL3MBTL1MEN1 | |
| SCHEMBL11653324 | 0.78 | KMT2A (0.41) | P2RX4POLBRXFP1SMN1; SMN2KMT2A | |
| SCHEMBL11658967 | 0.72 | POLB (0.43) | P2RX4CYP2C8CYP2D6CYP2C9ADRA2B | |
| SCHEMBL11656425 | 0.72 | POLB (0.43) | P2RX4POLBRXFP1SMN1; SMN2KMT2A | |
| SCHEMBL11771164 | 0.68 | POLB (0.50) | P2RX4CYP2C8CYP2D6CYP2C9ADRA2B | |
| SCHEMBL11657408 | 0.67 | ALDH1A1 (0.41) | P2RX4CYP2D6POLBRXFP1SMN1; SMN2 | |
| SCHEMBL11655829 | 0.67 | POLB (0.40) | P2RX4CYP2D6POLBRXFP1SMN1; SMN2 | |
| SCHEMBL29625922 | 0.65 | IDH1 (0.56) | P2RX4SMN1; SMN2KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4124581-A | FOR NATURAL AND SYNTHETIC FIBERS, COLORFAST | BAYER AKTIENGESELLSCHAFT (DE) | 1978-11-07 | — | — | US | disclosed |