SCHEMBL11659130

SCHEMBL11659130

ClCCc1ccc2[nH]nnc2c1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 1/20 0.30
TCF7L2 Q9NQB0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29746161 0.90 DRD2 (0.30)
SCHEMBL7127295 0.85
SCHEMBL241224 0.82 CNR1 (0.39)
SCHEMBL501616 0.81 MEN1 (0.39) CTNNB1
SCHEMBL28820454 0.81 IP6K1 (0.41)
SCHEMBL242265 0.79 HTR1A (0.41)
SCHEMBL242143 0.78 HTR1A (0.43)
SCHEMBL11432893 0.78 IGF1R (0.32)
SCHEMBL6365081 0.78 HTR1A (0.40)
SCHEMBL28988162 0.78 GRIK1 (0.33) CTNNB1TCF7L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4075014-A HYDROXYALKYLAMINE DEVELOPMENT ACCELERATOR; POSITIVES TETENAL PHOTOWERK WALTER GRABIG (DT) 1978-02-21 US disclosed