Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.51 |
| ▸ | NCOR1 | O75376 | 3/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.48 |
| ▸ | BCL2A1 | Q16548 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11644076 | 0.80 | HDAC1 (0.50) | HDAC3HDAC1HDAC2NPC1KDM4E | |
| SCHEMBL11630712 | 0.80 | MAPT (0.51) | MCL1BCL2A1MAPTNPC1CYP3A4 | |
| SCHEMBL11401717 | 0.79 | NPC1 (0.46) | HDAC3HDAC1HDAC2MAPTNPC1 | |
| SCHEMBL11659228 | 0.78 | NPC1 (0.45) | HDAC3HDAC1HDAC2NCOR1MAPT | |
| SCHEMBL11645107 | 0.77 | HDAC1 (0.46) | HDAC3HDAC1HDAC2NCOR1HDAC4 | |
| SCHEMBL24101771 | 0.76 | MCL1 (0.59) | HDAC3HDAC1HDAC2NCOR1HDAC4 | |
| SCHEMBL11652564 | 0.75 | LMNA (0.53) | MCL1BCL2A1BRD4ADORA3MEN1 | |
| SCHEMBL30468962 | 0.74 | POLB (0.55) | MCL1BCL2A1NPC1MAOAMAOB | |
| SCHEMBL11630533 | 0.74 | POLB (0.55) | MCL1BCL2A1NPC1MAOAMAOB | |
| SCHEMBL13577090 | 0.73 | MAOA (0.50) | MCL1BCL2A1NPC1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4072696-A | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity | SYNTEX (U.S.A.) INC. (US) | 1978-02-07 | — | — | US | disclosed |