Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 4/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | GPX4 | P36969 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11659033 | 0.92 | TP53 (0.66) | TP53TDP1KMT2AMEN1NR1I2 | |
| SCHEMBL11657353 | 0.87 | TP53 (0.61) | TP53TDP1KMT2AMEN1NR1I2 | |
| SCHEMBL11658557 | 0.85 | TP53 (0.63) | TP53TDP1KMT2AMEN1NR1I2 | |
| SCHEMBL3695063 | 0.84 | TP53 (0.66) | TP53TDP1KMT2AMEN1NR1I2 | |
| SCHEMBL131683 | 0.84 | TP53 (0.66) | TP53TDP1KMT2AMEN1NR1I2 | |
| SCHEMBL11653949 | 0.84 | TP53 (0.66) | TP53TDP1KMT2AMEN1NR1I2 | |
| SCHEMBL27976189 | 0.84 | TP53 (0.69) | TP53TDP1KMT2AMEN1NR1I2 | |
| SCHEMBL11655815 | 0.83 | ALDH1A1 (0.51) | TP53TDP1KMT2AMEN1NR1I2 | |
| SCHEMBL11413459 | 0.83 | TP53 (0.64) | TP53TDP1KMT2AMEN1NR1I2 | |
| SCHEMBL9614029 | 0.82 | TP53 (0.71) | TP53TDP1KMT2AMEN1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4126440-A | Hydroxamic acid derivatives for regulating plant growth | CIBA-GEIGY CORPORATION (US) | 1978-11-21 | — | — | US | disclosed |