Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 5/20 | 0.39 |
| ▸ | RXRB | P28702 | 5/20 | 0.39 |
| ▸ | RXRG | P48443 | 5/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.35 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11662833 | 0.99 | RXRA (0.38) | RXRARXRBRXRGHDAC3HDAC1 | |
| SCHEMBL11663428 | 0.99 | RXRA (0.40) | RXRARXRBRXRGHDAC3HDAC1 | |
| SCHEMBL11667478 | 0.95 | RXRA (0.37) | RXRARXRBRXRGHDAC3HDAC1 | |
| SCHEMBL11657247 | 0.89 | RXRB (0.36) | RXRARXRBRXRGHDAC8ALDH1A1 | |
| SCHEMBL11662830 | 0.87 | HDAC3 (0.36) | RXRARXRBRXRGHDAC3HDAC1 | |
| Potassium Ion SCHEMBL11664127 | 0.85 | HDAC3 (0.37) | RXRARXRBRXRGHDAC3HDAC1 | |
| SCHEMBL11742489 | 0.83 | HPN (0.50) | NR5A2NR5A1MAPTKMT2A | |
| SCHEMBL11658758 | 0.82 | MAPT (0.41) | RXRARXRBRXRGHDAC3HDAC1 | |
| SCHEMBL11741056 | 0.82 | HPN (0.49) | NR5A2NR5A1MAPTKMT2A | |
| SCHEMBL11664373 | 0.78 | HDAC3 (0.33) | HDAC3HDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4067998-A | HYPOLIPIDEMIC AGENTS | THE DOW CHEMICAL COMPANY (US) | 1978-01-10 | — | — | US | claimed |
| US-4067998-A | HYPOLIPIDEMIC AGENTS | THE DOW CHEMICAL COMPANY (US) | 1978-01-10 | — | — | US | disclosed |