Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRB | P28702 | 10/20 | 0.36 |
| ▸ | RXRA | P19793 | 9/20 | 0.36 |
| ▸ | RXRG | P48443 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CD69 | Q07108 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11667478 | 0.91 | RXRA (0.37) | RXRBRXRARXRGALDH1A1GABRA1 | |
| SCHEMBL11660641 | 0.89 | RXRA (0.39) | RXRBRXRARXRGALDH1A1SLC13A5 | |
| SCHEMBL11662833 | 0.88 | RXRA (0.38) | RXRBRXRARXRGALDH1A1SLC13A5 | |
| SCHEMBL11663428 | 0.88 | RXRA (0.40) | RXRBRXRARXRGALDH1A1SMN1; SMN2 | |
| SCHEMBL11661830 | 0.82 | CNR2 (0.35) | ALDH1A1SMN1; SMN2CYP3A4MAPTMAPK1 | |
| SCHEMBL11734771 | 0.81 | HPN (0.54) | MAPTALOX15 | |
| SCHEMBL11662830 | 0.76 | HDAC3 (0.36) | RXRBRXRARXRGALDH1A1GABRA1 | |
| SCHEMBL11663579 | 0.75 | RXRB (0.46) | RXRBRXRARXRGALDH1A1GABRA1 | |
| SCHEMBL3823413 | 0.75 | ESR1 (0.42) | ALDH1A1CYP3A4BLMTDP1 | |
| SCHEMBL3828827 | 0.74 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2CYP3A4MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4067998-A | HYPOLIPIDEMIC AGENTS | THE DOW CHEMICAL COMPANY (US) | 1978-01-10 | — | — | US | claimed |
| US-4067998-A | HYPOLIPIDEMIC AGENTS | THE DOW CHEMICAL COMPANY (US) | 1978-01-10 | — | — | US | disclosed |