Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | AOC2 | O75106 | 1/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11664301 | 0.81 | CA4 (0.33) | PPARAALDH1A1 | |
| SCHEMBL28993188 | 0.74 | GAA (0.36) | NFE2L2GAACASRMAOAMAOB | |
| SCHEMBL27841641 | 0.72 | GAA (0.43) | NFE2L2GAACASRMAOAMAOB | |
| SCHEMBL11660365 | 0.71 | GAA (0.34) | NFE2L2GAACASRMAOBPPARA | |
| SCHEMBL11662822 | 0.71 | MAOB (0.41) | MAOBPPARAKDM4EALDH1A1 | |
| SCHEMBL11518124 | 0.70 | CASR (0.36) | NFE2L2GAACASRMAOAMAOB | |
| SCHEMBL11661682 | 0.70 | SSTR4 (0.39) | MAOAMAOBAOC2DAO | |
| SCHEMBL11664095 | 0.70 | PGR (0.37) | MAOBKDM4E | |
| SCHEMBL4977051 | 0.69 | NFE2L2 (0.41) | NFE2L2GAACASRMAOAMAOB | |
| SCHEMBL11517918 | 0.69 | NFE2L2 (0.36) | NFE2L2GAACASRMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4099014-A | BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4033989-A | 9-Deoxy-PGF2 Analogs | THE UPJOHN COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
| US-4016184-A | PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1977-04-05 | — | — | US | disclosed |