SCHEMBL11664855

SCHEMBL11664855

Cc1ccc(N=C=O)c2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.52
CYP3A4 P08684 5/20 0.50
TRPA1 O75762 1/20 0.48
CYP2A6 P11509 3/20 0.41
ALDH1A1 P00352 4/20 0.38
HPGD P15428 3/20 0.38
TDP1 Q9NUW8 3/20 0.38
GLO1 Q04760 2/20 0.36
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
TSHR P16473 3/20 0.33
HSD17B10 Q99714 2/20 0.33
MAPT P10636 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
CCR2 P41597 2/20 0.33
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2A Q12879 1/20 0.33
GRIN2B Q13224 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12206125 0.88 CYP3A4 (0.61) CYP1A2CYP3A4TRPA1CYP2A6ALDH1A1
SCHEMBL27066 0.87 CYP3A4 (0.50) CYP1A2CYP3A4TRPA1ALDH1A1HPGD
SCHEMBL29405309 0.87 CYP3A4 (0.50) CYP1A2CYP3A4TRPA1ALDH1A1HPGD
SCHEMBL11382980 0.81 CYP3A4 (0.45) CYP1A2CYP3A4TRPA1ALDH1A1HPGD
SCHEMBL28189098 0.81 CYP3A4 (0.45) CYP1A2CYP3A4TRPA1ALDH1A1HPGD
SCHEMBL6390165 0.80 ALDH1A1 (0.55) CYP1A2CYP3A4CYP2A6ALDH1A1HPGD
SCHEMBL22210 0.78 CYP3A4 (0.62) CYP1A2CYP3A4TRPA1ALDH1A1HPGD
SCHEMBL29370250 0.78 CYP3A4 (0.62) CYP1A2CYP3A4TRPA1ALDH1A1HPGD
SCHEMBL332723 0.78 CYP3A4 (0.53) CYP1A2CYP3A4TRPA1CYP2A6ALDH1A1
SCHEMBL31249481 0.78 CYP3A4 (0.53) CYP1A2CYP3A4TRPA1CYP2A6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100500696-C Synthesis process of carbamido carboxymethyl chitosan INST OCEANOLOGY CHINESE ACAD (CN) 2009-06-17 CN disclosed
CN-1740203-A A kind of synthetic method of carbamido carboxymethyl chitosan INST OCEANOLOGY CHINESE ACAD (CN) 2006-03-01 CN disclosed
US-4124545-A Carbamic acid esters as catalysts for trimerization of isocyanates BAYER AKTIENGESELLSCHAFT (DE) 1978-11-07 US disclosed
US-3985789-A Carbamic acid esters BAYER AKTIENGESELLSCHAFT (DT) 1976-10-12 US disclosed