Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | GPR17 | Q13304 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11665975 | 0.82 | APEX1 (0.60) | APEX1GPR17MEN1KMT2APGR | |
| SCHEMBL7336916 | 0.79 | ALDH1A1 (0.55) | GPR17MEN1KMT2ASTSCYP3A4 | |
| SCHEMBL6932664 | 0.78 | MEN1 (0.67) | GPR17MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6554508 | 0.78 | F2 (0.49) | MEN1KMT2APGRSTSCYP3A4 | |
| SCHEMBL7193238 | 0.76 | APEX1 (1.00) | APEX1MEN1KMT2APGRTDP1 | |
| SCHEMBL11660308 | 0.75 | ALDH1A1 (0.57) | GPR17KMT2AP2RY2ALDH1A1HTT | |
| SCHEMBL29812596 | 0.75 | STS (0.51) | MEN1KMT2ASTSHSD17B10CYP3A4 | |
| SCHEMBL1243178 | 0.75 | STS (0.51) | MEN1KMT2ASTSHSD17B10CYP3A4 | |
| SCHEMBL11849091 | 0.74 | APEX1 (0.67) | APEX1GPR17MEN1KMT2APGR | |
| SCHEMBL21496179 | 0.74 | STS (0.42) | GPR17MEN1KMT2ASTSHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4112083-A | NEMATOCIDE, INSECTICIDE, MITICIDE, FUNGICIDE | ROHM AND HAAS COMPANY (US) | 1978-09-05 | — | — | US | disclosed |
| US-4053499-A | PESTICIDES | ROHM AND HAAS COMPANY (US) | 1977-10-11 | — | — | US | disclosed |
| US-3975420-A | PESTICIDE | ROHM AND HAAS COMPANY (US) | 1976-08-17 | — | — | US | disclosed |