Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 19/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.53 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1167411 | 0.90 | HCRTR2 (0.59) | HCRTR2HCRTR1 | |
| SCHEMBL1166534 | 0.90 | HCRTR2 (0.51) | HCRTR2HCRTR1 | |
| SCHEMBL1167459 | 0.85 | HCRTR2 (0.65) | HCRTR2HCRTR1 | |
| SCHEMBL1166709 | 0.83 | HCRTR2 (0.43) | HCRTR2HCRTR1 | |
| SCHEMBL1166943 | 0.83 | HCRTR2 (0.48) | HCRTR2HCRTR1TAS2R8 | |
| SCHEMBL1167207 | 0.78 | HCRTR2 (0.57) | HCRTR2HCRTR1TAS2R8 | |
| SCHEMBL1167197 | 0.76 | HCRTR2 (0.45) | HCRTR2HCRTR1 | |
| SCHEMBL1167284 | 0.76 | HCRTR2 (0.69) | HCRTR2HCRTR1 | |
| SCHEMBL1166196 | 0.74 | HCRTR2 (0.62) | HCRTR2HCRTR1 | |
| SCHEMBL1168158 | 0.74 | FPR2 (0.49) | HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110034516-A1 | AMINOPYRAZOLE DERIVATIVES | ACTELION (CH) | 2011-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034516-A1 | AMINOPYRAZOLE DERIVATIVES | CYP3A43, CYP1A2, CYP3A5 | HCRTR2 2700/4885HCRTR1 2862/4885TAS2R8 1765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.