Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.61 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12102467 | 0.86 | LMNA (0.65) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| SCHEMBL4637559 | 0.84 | LMNA (0.61) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| SCHEMBL10459087 | 0.84 | ASAH1 (0.72) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| SCHEMBL18798677 | 0.83 | LMNA (0.61) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| SCHEMBL21130047 | 0.82 | LMNA (0.51) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| SCHEMBL17899487 | 0.82 | LMNA (0.67) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| SCHEMBL11251920 | 0.81 | LMNA (0.68) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| SCHEMBL11601229 | 0.80 | ASAH1 (0.80) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| SCHEMBL17897713 | 0.80 | LMNA (0.67) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| SCHEMBL4637266 | 0.79 | LMNA (0.48) | LMNACYP3A4CYP2D6MAPK3ASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-53028183-A | — | — | None | — | — | JP | disclosed |
| JP-S5328183-A | 1-CARBAMOYL-5-FLUOROURACIL DERIVATIVES AND THIER PREPARATION | MITSUI TOATSU CHEM INC | 1978-03-16 | — | — | JP | disclosed |