Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.61 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10459087 | 0.84 | ASAH1 (0.72) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| SCHEMBL18798677 | 0.84 | LMNA (0.61) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| SCHEMBL11665245 | 0.84 | LMNA (0.61) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| SCHEMBL11239635 | 0.83 | LMNA (0.70) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| SCHEMBL17278298 | 0.82 | LMNA (0.69) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| SCHEMBL11251920 | 0.81 | LMNA (0.68) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| SCHEMBL29001286 | 0.81 | ASAH1 (0.75) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| SCHEMBL11601229 | 0.81 | ASAH1 (0.80) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| SCHEMBL9664618 | 0.81 | LMNA (0.67) | LMNACYP3A4CYP2D6MAPK3ASAH1 | |
| Acetic Acid SCHEMBL28886347 | 0.80 | ASAH1 (0.74) | LMNACYP3A4CYP2D6MAPK3ASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1939186-A1 | 5-Fluorouracil derivatives and their use for the treatment of cancer | Sulfidris S.r.l. (IT) | 2008-07-02 | — | — | EP | disclosed |