Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11661113 | 0.87 | ALDH1A1 (0.64) | ALDH1A1PKMMAPK1MAPTPOLB | |
| SCHEMBL14515285 | 0.87 | MAPT (0.59) | ALDH1A1PKMMAPK1MAPTPOLB | |
| SCHEMBL11664357 | 0.83 | KMT2A (0.64) | ALDH1A1PKMMAPK1MAPTPOLB | |
| SCHEMBL11664728 | 0.83 | NPC1 (0.53) | ALDH1A1PKMMAPK1MAPTPOLB | |
| SCHEMBL7270186 | 0.82 | ALDH1A1 (0.68) | ALDH1A1PKMMAPK1MAPTPOLB | |
| SCHEMBL31257119 | 0.82 | ADRB2 (0.68) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL12835269 | 0.81 | CYP1A2 (0.64) | ALDH1A1MAPTPOLBNPC1MEN1 | |
| SCHEMBL11665104 | 0.81 | NPC1 (0.51) | ALDH1A1PKMMAPK1MAPTPOLB | |
| SCHEMBL6630532 | 0.80 | MAPT (0.64) | ALDH1A1MAPTMEN1KMT2AADRB2 | |
| SCHEMBL15060886 | 0.80 | ALDH1A1 (0.70) | ALDH1A1PKMMAPK1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4123614-A | USED IN DETECTION AND MEASUREMENT OF BIOLOGICAL SYSTEMS AND/OR COMPONENTS | SYNTEX (U.S.A.) INC. (US) | 1978-10-31 | — | — | US | disclosed |