Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | S100A4 | P26447 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8692154 | 0.87 | TDP1 (0.47) | PTPRCALDH1A1S100A4BCHEACHE | |
| SCHEMBL27287105 | 0.85 | ALDH1A1 (0.51) | PTPRCALDH1A1S100A4BCHEACHE | |
| SCHEMBL7808231 | 0.85 | ALDH1A1 (0.49) | PTPRCALDH1A1S100A4BCHEACHE | |
| SCHEMBL7201063 | 0.85 | ALDH1A1 (0.59) | PTPRCALDH1A1S100A4MAPTMEN1 | |
| SCHEMBL10915670 | 0.82 | HTT (0.53) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL5061932 | 0.82 | EIF4E (0.49) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL8578001 | 0.78 | CYP1A2 (0.52) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL1285054 | 0.77 | APP (0.60) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL28855265 | 0.76 | CLK1 (0.50) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL403505 | 0.76 | MAPT (0.64) | ALDH1A1ACHEMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4119629-A | CENTRAL NERVOUS SYSTEM DEPRESSANTS, WEIGHT CONTROL AGENTS | MILLER RICHARD FOSTER | 1978-10-10 | — | — | US | disclosed |