Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 9/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11660779 | 0.85 | MEN1 (0.69) | GAACYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL11660947 | 0.83 | GAA (0.56) | GAACYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL25420635 | 0.75 | LMNA (0.44) | GAACYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL28341045 | 0.72 | ALDH1A1 (0.43) | GAACYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL11660768 | 0.72 | MEN1 (0.66) | GAACYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL11012145 | 0.71 | MEN1 (0.65) | GAACYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL8571164 | 0.71 | TSHR (0.47) | GAACYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL11659247 | 0.71 | MEN1 (0.64) | GAACYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL11660759 | 0.71 | MEN1 (0.61) | GAACYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL18025749 | 0.71 | BRD4 (0.57) | GAAMEN1KMT2AATMTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4099002-A | QUINAZOLINONE DERIVATIVES AND A PROCESS FOR PRODUCTION THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1978-07-04 | — | — | US | disclosed |