Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9719786 | 0.85 | AKR1C3 (0.51) | AKR1C3PTGS1NPC1RAB9APOLB | |
| SCHEMBL3936634 | 0.85 | AKR1C3 (0.51) | AKR1C3PTGS1NPC1RAB9APOLB | |
| SCHEMBL7319456 | 0.83 | AKR1C3 (0.50) | AKR1C3PTGS1NPC1RAB9APOLB | |
| SCHEMBL10697799 | 0.82 | PKM (0.56) | AKR1C3PTGS1NPC1RAB9APOLB | |
| SCHEMBL6829887 | 0.80 | MAPT (0.50) | CYP2C9HDAC8KMT2ACYP2D6ALDH1A1 | |
| SCHEMBL11318442 | 0.80 | AKR1C3 (0.46) | AKR1C3PTGS1NPC1RAB9APOLB | |
| SCHEMBL15557683 | 0.80 | POLB (0.53) | AKR1C3PTGS1NPC1RAB9APOLB | |
| SCHEMBL548030 | 0.79 | CETP (0.51) | AKR1C3PTGS1NPC1RAB9APOLB | |
| SCHEMBL10719301 | 0.78 | AKR1C3 (0.49) | AKR1C3PTGS1NPC1RAB9APOLB | |
| SCHEMBL5671239 | 0.78 | CYP2C9 (0.54) | AKR1C3PTGS1NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-53082750-A | — | — | None | — | — | JP | disclosed |
| JP-S5382750-A | ALPHA-THIO-ALPHA-(M-PHEHOXYPHENYL)PROPIONIC ACID DERIVS. | SAGAMI CHEM RES CENTER | 1978-07-21 | — | — | JP | disclosed |