Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1167161 | 0.91 | HCRTR2 (0.62) | HCRTR2HCRTR1 | |
| SCHEMBL1166829 | 0.90 | HCRTR2 (0.62) | HCRTR2HCRTR1 | |
| SCHEMBL1166943 | 0.88 | HCRTR2 (0.48) | HCRTR2HCRTR1 | |
| SCHEMBL1166364 | 0.87 | HCRTR2 (0.72) | HCRTR2HCRTR1 | |
| SCHEMBL1165878 | 0.85 | HCRTR2 (0.77) | HCRTR2HCRTR1 | |
| SCHEMBL1166551 | 0.84 | FPR2 (0.49) | HCRTR2 | |
| SCHEMBL1166816 | 0.83 | HCRTR2 (0.69) | HCRTR2HCRTR1 | |
| SCHEMBL1167459 | 0.82 | HCRTR2 (0.65) | HCRTR2HCRTR1 | |
| SCHEMBL1166493 | 0.79 | HCRTR2 (0.54) | HCRTR2HCRTR1 | |
| SCHEMBL1166938 | 0.78 | TAS2R8 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110034516-A1 | AMINOPYRAZOLE DERIVATIVES | ACTELION (CH) | 2011-02-10 | — | — | US | claimed |
| US-20110034516-A1 | AMINOPYRAZOLE DERIVATIVES | ACTELION (CH) | 2011-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034516-A1 | AMINOPYRAZOLE DERIVATIVES | CYP3A43, CYP1A2, CYP3A5 | HCRTR2 2700/4885HCRTR1 2862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.