Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.38 |
| ▸ | HTR3B | O95264 | 2/20 | 0.38 |
| ▸ | HTR3A | P46098 | 2/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11611733 | 0.86 | TAAR1 (0.42) | TAAR1TSHRRECQLPNMTTRPV1 | |
| SCHEMBL11613112 | 0.80 | HTR3E (0.42) | TAAR1TSHRRECQLPNMTNPC1 | |
| SCHEMBL11515564 | 0.76 | TSHR (0.40) | TAAR1TSHRRECQLPNMTNPC1 | |
| SCHEMBL10451551 | 0.73 | PNMT (0.54) | TAAR1PNMTHTR3EHTR3BHTR3A | |
| SCHEMBL11664309 | 0.71 | PNMT (0.41) | TAAR1TSHRRECQLPNMTTRPV1 | |
| SCHEMBL24863785 | 0.70 | PNMT (0.47) | TAAR1PNMTHTR3EHTR3BHTR3A | |
| SCHEMBL11616304 | 0.70 | HTR2A (0.46) | TAAR1PNMTMEN1KMT2ACETP | |
| SCHEMBL11614808 | 0.70 | PNMT (0.46) | TAAR1TSHRRECQLPNMTHTR3E | |
| SCHEMBL11615168 | 0.68 | CYP3A4 (0.44) | TAAR1PNMTHTR3EHTR3BHTR3A | |
| SCHEMBL11517656 | 0.68 | TSHR (0.44) | TAAR1TSHRRECQLPNMTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4073808-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-02-14 | — | — | US | disclosed |