Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | HRH1 | P35367 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7175620 | 0.83 | CHRNB2 (0.50) | MAPTHTR2AHRH1TDP1POLB | |
| Hydrochloric Acid SCHEMBL19809919 | 0.81 | CHRNB2 (0.49) | HTR2AHRH1TDP1POLBSIGMAR1 | |
| SCHEMBL12126065 | 0.80 | SIGMAR1 (0.44) | HTR2AHRH1TDP1POLBSIGMAR1 | |
| SCHEMBL11184514 | 0.80 | TP53 (0.49) | TP53MAPTSLC6A2SLC6A4HTR2A | |
| SCHEMBL11218712 | 0.80 | SLC6A2 (0.51) | TP53MAPTSLC6A2SLC6A4HTR2A | |
| SCHEMBL11190126 | 0.80 | HTR2A (0.60) | TP53MAPTSLC6A2SLC6A4HTR2A | |
| SCHEMBL27574450 | 0.79 | TP53 (0.48) | TP53MAPTSLC6A2SLC6A4HTR2A | |
| SCHEMBL11709922 | 0.78 | HTR2A (0.40) | MAPTSLC6A2SLC6A4HTR2AHRH1 | |
| SCHEMBL2258445 | 0.78 | SIGMAR1 (0.39) | MAPTSLC6A2SLC6A4HTR2AHRH1 | |
| SCHEMBL28143609 | 0.78 | SIGMAR1 (0.42) | MAPTHTR2AHRH1POLBSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101541-A | DYES FOR POLYESTERS OR POLYPROPYLENE | CIBA-GEIGY CORPORATION (US) | 1978-07-18 | — | — | US | disclosed |