Acrylic Acid

Acrylic Acid

SCHEMBL11668481

C=CC(=O)O.CCC(C)(CC)C(N)=O.N

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.42
ALDH1A1 P00352 2/20 0.35
TSHR P16473 2/20 0.35
FGFR4 P22455 1/20 0.35
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
HTT P42858 1/20 0.31
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL276842 0.82
Pivalamide SCHEMBL11668554 0.80 LMNA (0.53) LMNAALDH1A1TSHRFGFR4ALOX15
Acrylic Acid SCHEMBL11600976 0.80 LMNA (0.53) LMNAALDH1A1TSHRFGFR4ALOX15
Acrylic Acid SCHEMBL4922885 0.78 LMNA (0.50) LMNAALDH1A1TSHRFGFR4ALOX15
Acrylic Acid SCHEMBL28101959 0.78 LMNA (0.50) LMNAALDH1A1TSHRALOX15HSD17B10
Acrylic Acid SCHEMBL4563264 0.77 LMNA (0.56) LMNAALDH1A1TSHRFGFR4ALOX15
Acrylic Acid SCHEMBL30477513 0.77 LMNA (0.56) LMNAALDH1A1TSHRFGFR4ALOX15
Acrylic Acid SCHEMBL29550213 0.77 LMNA (0.56) LMNAALDH1A1TSHRFGFR4ALOX15
Acrylic Acid SCHEMBL1015243 0.77 LMNA (0.56) LMNAALDH1A1TSHRFGFR4ALOX15
Acrylic Acid SCHEMBL29393748 0.77 LMNA (0.56) LMNAALDH1A1TSHRFGFR4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4012445-A Beta-amino carbonyl catalysts for polyurethane preparation UNION CARBIDE CORPORATION (US) 1977-03-15 US disclosed
US-4011223-A POLYMERIZATION CATALYSTS, POLYURETHANES UNION CARBIDE CORPORATION (US) 1977-03-08 US disclosed