SCHEMBL11668643

SCHEMBL11668643

CCCNC(=O)n1ccc(=O)[nH]c1=O

nearest known ligand 0.83

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ASAH1 Q13510 3/20 0.46
LMNA P02545 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
MAPK3 P27361 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
SQOR Q9Y6N5 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7784441 0.88 ASAH1 (0.61) ASAH1LMNACYP3A4CYP2D6MAPK3
SCHEMBL7058609 0.81 ALDH1A1 (0.43) LMNA
SCHEMBL15538622 0.78 CA1 (0.41) ASAH1
SCHEMBL7542248 0.77 ALDH1A1 (0.40) LMNA
SCHEMBL15598615 0.77 ALDH1A1 (0.39) ASAH1LMNA
SCHEMBL15537799 0.77 ALDH1A1 (0.39) ASAH1LMNA
SCHEMBL15537994 0.76 ASAH1 (0.55) ASAH1
SCHEMBL15598464 0.76 ASAH1 (0.48) ASAH1
SCHEMBL15538910 0.76 ASAH1 (0.54) ASAH1
SCHEMBL1526612 0.75 CRBN (0.47) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-52148084-A None JP disclosed
JP-S52148084-A 1-CARBAMOYLURACILS AND THEIR PREPARATION MITSUI TOATSU CHEM INC 1977-12-08 JP disclosed