Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11668643 | 0.88 | ASAH1 (0.46) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL15598464 | 0.82 | ASAH1 (0.48) | ASAH1 | |
| SCHEMBL15538910 | 0.82 | ASAH1 (0.54) | ASAH1 | |
| SCHEMBL15537994 | 0.80 | ASAH1 (0.55) | ASAH1 | |
| SCHEMBL15537792 | 0.80 | ASAH1 (0.49) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL15538622 | 0.79 | CA1 (0.41) | ASAH1 | |
| SCHEMBL15538164 | 0.78 | ASAH1 (0.50) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL15538693 | 0.77 | ASAH1 (0.71) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL15538170 | 0.77 | MLYCD (0.41) | — | |
| SCHEMBL15539115 | 0.77 | NAMPT (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55019245-A | — | — | None | — | — | JP | disclosed |
| EP-2875006-A1 | ACID CERAMIDASE INHIBITORS AND THEIR USE AS MEDICAMENTS | Fondazione Istituto Italiano Di Tecnologia (IT) | 2015-05-27 | — | — | EP | disclosed |
| WO-2013178576-A1 | ACID CERAMIDASE INHIBITORS AND THEIR USE AS MEDICAMENTS | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2013-12-05 | — | — | WO | disclosed |
| JP-2001064179-A | ANTICANCER AGENT INCLUDING CARBAMOYL DERIVATIVE AS ACTIVE INGREDIENT | MITSUI CHEMICALS INC | 2001-03-13 | — | — | JP | disclosed |
| US-4650801-A | CYTOSINE TO INHIBIT DECOMPOSITION | TAIHO PHARMACEUTICAL COMPANY, LTD. (JP) | 1987-03-17 | — | — | US | disclosed |
| EP-0068268-B1 | ENHANCER OF ANTI-TUMOUR EFFECT | Yamasa Shoyu Kabushiki Kaisha (JP) | 1985-05-02 | — | — | EP | disclosed |
| EP-0048022-B1 | ENHANCER OF ANTI-TUMOR EFFECT | Yamasa Shoyu Kabushiki Kaisha (JP) | 1985-01-09 | — | — | EP | disclosed |
| EP-0079054-A1 | Enhancer of antitumor effect | Yamasa Shoyu Kabushiki Kaisha (JP) | 1983-05-18 | — | — | EP | disclosed |
| JP-S5519245-A | ANTI-MALIGNANT TUMOR AGENT COMPOSITION | TAIHO YAKUHIN KOGYO KK | 1980-02-09 | — | — | JP | disclosed |