Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL11843237 | 0.85 | KDM4E (0.55) | KDM4EKMT2AMAPTLMNAGPR35 | |
| SCHEMBL11838053 | 0.83 | KDM4E (0.51) | KDM4EKMT2AMAPTLMNAGPR35 | |
| SCHEMBL11842018 | 0.82 | KDM4E (0.69) | KDM4EKMT2AMAPTLMNAGPR35 | |
| SCHEMBL11834715 | 0.82 | KDM4E (0.50) | KDM4EKMT2AMAPTLMNAGPR35 | |
| SCHEMBL11834582 | 0.81 | KMT2A (0.55) | KDM4EKMT2AMAPTLMNAHPGD | |
| Hydrochloric Acid SCHEMBL11833084 | 0.80 | KMT2A (0.53) | KDM4EKMT2AMAPTLMNAHPGD | |
| SCHEMBL121334 | 0.75 | L3MBTL1 (0.59) | KDM4EKMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL11835514 | 0.73 | KDM4E (0.50) | KDM4EKMT2AMAPTLMNAGPR35 | |
| SCHEMBL11669099 | 0.73 | KDM4E (0.52) | KDM4EKMT2AMAPTLMNAHPGD | |
| Hydrochloric Acid SCHEMBL11835491 | 0.72 | KDM4E (0.49) | KDM4EKMT2AMAPTLMNAGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-52122366-A | — | — | None | — | — | JP | disclosed |
| JP-S52122366-A | INDAZOLE DERIVATIVES | CHUGAI PHARMACEUT CO LTD | 1977-10-14 | — | — | JP | disclosed |