Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | FER | P16591 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | MARK3 | P27448 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.38 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11838053 | 0.86 | KDM4E (0.51) | KDM4EKMT2AMEN1TSHRMAPT | |
| SCHEMBL11842018 | 0.85 | KDM4E (0.69) | KDM4EKMT2AMEN1TSHRMAPT | |
| SCHEMBL11834582 | 0.84 | KMT2A (0.55) | KDM4EKMT2ATSHRMAPTLMNA | |
| Hydrochloric Acid SCHEMBL11837379 | 0.84 | KDM4E (0.67) | KDM4EKMT2AMEN1TSHRMAPT | |
| Hydrochloric Acid SCHEMBL11833084 | 0.83 | KMT2A (0.53) | KDM4EKMT2ATSHRMAPTLMNA | |
| SCHEMBL11669095 | 0.82 | KDM4E (0.56) | KDM4EKMT2AMEN1TSHRMAPT | |
| Oxalic Acid SCHEMBL11843237 | 0.81 | KDM4E (0.55) | KDM4EKMT2AMEN1TSHRMAPT | |
| SCHEMBL11835514 | 0.76 | KDM4E (0.50) | KDM4EKMT2AMEN1TSHRMAPT | |
| Hydrochloric Acid SCHEMBL11835491 | 0.75 | KDM4E (0.49) | KDM4EKMT2AMEN1TSHRMAPT | |
| SCHEMBL4499277 | 0.73 | L3MBTL1 (0.59) | KDM4EKMT2AMEN1DCLK1PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3994890-A | TRANQUILIZERS, ANTIDEPRESSANTS, ANTIINFLAMMATORY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) | 1976-11-30 | — | — | US | claimed |