Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.53 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HK1 | P19367 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | GALK1 | P51570 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acridan SCHEMBL29405807 | 0.78 | MAPT (0.65) | AHRPDK2MAPTNPC1KDM4E | |
| Acridan SCHEMBL183367 | 0.78 | MAPT (0.65) | AHRPDK2MAPTNPC1KDM4E | |
| Acridan SCHEMBL29446489 | 0.78 | MAPT (0.65) | AHRPDK2MAPTNPC1KDM4E | |
| Acridan SCHEMBL20594012 | 0.78 | MAPT (0.65) | AHRPDK2MAPTNPC1KDM4E | |
| SCHEMBL6249305 | 0.78 | AHR (0.61) | AHRPDK2MAPTNPC1KDM4E | |
| SCHEMBL4156077 | 0.76 | AHR (0.59) | AHRPDK2MAPTNPC1KDM4E | |
| Acridan SCHEMBL10813635 | 0.75 | MAPT (0.62) | AHRPDK2MAPTNPC1KDM4E | |
| SCHEMBL4571016 | 0.75 | MAPT (0.62) | AHRPDK2MAPTNPC1KDM4E | |
| Acridan SCHEMBL15412652 | 0.75 | MAPT (0.62) | AHRPDK2MAPTNPC1KDM4E | |
| Acridan SCHEMBL29006126 | 0.75 | MAPT (0.62) | AHRPDK2MAPTNPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4024127-A | Process for the preparation of 5-alkyl-10-amino-dihydrodibenzoazepines | RHONE-POULENC S.A. (FR) | 1977-05-17 | — | — | US | claimed |
| US-4024127-A | Process for the preparation of 5-alkyl-10-amino-dihydrodibenzoazepines | RHONE-POULENC S.A. (FR) | 1977-05-17 | — | — | US | disclosed |
| US-4024127-A | Process for the preparation of 5-alkyl-10-amino-dihydrodibenzoazepines | RHONE-POULENC S.A. (FR) | 1977-05-17 | — | — | US | disclosed |